Pharmaceutical Peptides-API and Intermediates-Enzymesubstrates/Inhibitors

SM Biochemicals LLC

Supplier of Fluoromethyl Ketones (FMK), Difluorophenoxymethylketone (Q-VD-OPH), Caspase/
Apoptosis Detection Kits, Calpain Inhibitors, Cathepsin Inhibitors, Antiviral Peptide inhibitor
(Picornavirus 2A Proteinases), Peptide Aldehyde (CHO), Caspase / Apoptosis Inhibitors and
Substrates, Diazomethylketone Inhibitors, AMC/ AFC/PNA/ Cresyl voilet/ Thiobenzyl Substrates (SBzl),
wide variety of peptides for both research and bulk pharmeceutical trials. Active Pharmaceutical
Ingredients, Custom Synthesis of Peptide and Organic molecules.

Q-VD-OPH, Z-VD-OPH, Boc-D-OPH, Z-DEVD-OPH, Z-VAD(OMe)-FMK, Z-VAD-FMK( non methylated)
Boc-D-FMK,Z-DEVD-FMK, Z-IETD-FMK, Z-LEHD-FMK, Z-VEID-FMK, Z-AEVD-FMK, Z-VDVAD-FMK,
Z-LEVD-FMK,Z-ATAD-FMK, Biotin-VAD-FMK, Biotin-DEVD-FMK, Z-FA-FMK, Biotin-FA-FMK, Z-FF-FMK,
Z-LLY-FMK, Z-VAM-FMK, FITC-VAD-FMK, FAM-VAD-FMK, FAM-DEVD-FMK, SR-VAD-FMK, SR-DEVD-FMK,
CASPASE / APOPTOSIS INHIBITORS AND DETECTION KITS CATHEPSIN, CALPAIN INHIBITORS, PEPTIDE
ALDEHYDE INHIBITORS, FLUOROGENIC (AMC, AFC), GLY-PHE-DIAZOMETHYLKETONE, CHROMOGENIC
( PNA ) SUBSTRATES.

CRESYL VOILET SUBSTRATES ( A new cell permeable fluorogenic substrate) THIOBENZYL ESTER
(SBzl) SUBSTRATES.

SM Biochemicals offers a wide variety of peptides including Adrenocorticotropic Hormone(ACTH),
Adrenomedullins, ADAM Substrate, Agatoxin IVa, Akt Substrate, All D Beta Amyloid, Alpha MSH, Amylin,
Amyloid, Angiotensin, APP, a great number of Beta Amyloids which have been found to offer useful
tools in Alzheimer's research. Bradykinin, Calcitonin,Casein Kinase, Cecropin B,Cecropin P1,porcine,
Corticotropin, Endothelins, Endothelin Antagonists, Exendin 3,Enzyme Inhibitors, Fibrinogen Binding,
Fibrinopeptide, Flag Peptide, Furin InhibitorII,Galanin, Galantide, Gamma Secretase Inhibitor, Gastric
Inhibitory Peptide, human / GIP, human, Gastrin, Gastrin Releasing Peptide, human / GRP, Ghrelin,
Glucagon,Growth Hormone Releasing Factor, H.I.V. -1 Protease, Hepatitis C Virus, HIVSubstrate IV, HIV
Substrate IV Inhibitor I, Humanin, KISS, Leumorphin, LH-RH Free Acid, Locustapyrokinin, MG-132/
Proteosome inhibitor, MMP Substrates and Inhibitors, MOG Protein, Motlin Peptides, Myosin, MZ
Peptides, Neuropeptide, Neurotensin, NFF2 MMP subsrates, Non A Beta component Amyloid, Obestatin,
Oxerin A and Oxerin B ( Human), Orntide, Oxyntomodulin, PACAP, Pancreastatin, Pancreatic
polypeptide, Parathyroid Hormone,PKA Inhibitor and Substrate, Plasminogen activator substrate,
Protein Kinase, PTH Peptide/Protein, PYY Peptide/Protein, Sarafotoxin peptides, Somatostatin peptides,
Syntide, TNF converting enzyme substrate, Tyrosine specific protein kinase, Vasoactive intestinal
constrictor, VIP peptides, VIP Antagonist, VIP Receptor, Xenopsin.

We provide peptides for both research and bulk pharmeceutical trials. A staff with decades of
experience in peptide chemistry will help you with the design and synthesis of your custom peptides
and with the technical information necessary to help you optimize your research results.

Active Pharmaceutical Ingredients ( APIs and Intermediates). Pharmaceutically active peptides.

Call our number (714)993-9461 or (925)876-3111 or email at info@smbiochemicals.com

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Catalog #

Peptide Name

Sequence

Size

Price ( $ )

SM645-50

Amylin, rat

Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg
-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-A
sn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-
Gly-Ser-Asn-Thr-Tyr-NH2

0.5 MG

195

SM645-50

Amylin, rat

Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg
-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-A
sn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-
Gly-Ser-Asn-Thr-Tyr-NH2

1 MG

325

SM641-81

Amyloid Blocker

Acetyl-Gln-Lys-Leu-Val-Phe-Phe-NH2

5 MG

140

SM641-64

Amyloid Fragment
(Pro18,Asp21)
(17-21)

Leu-Pro-Phe-Phe-Asp-OH

5 MG

160

SM641-87

Amyloid Precursor

7-Methoxycoumarin-4acetyl-Ser-Glu-Val-Asn-
Leu-Asp-Ala-Glu-Phe-Arg-e-DNP-Lys-Arg-Arg-
NH2

1 MG

195

SM641-87

Amyloid Precursor

7-Methoxycoumarin-4acetyl-Ser-Glu-Val-Asn-
Leu-Asp-Ala-Glu-Phe-Arg-e-DNP-Lys-Arg-Arg-
NH2

5 MG

650

SM131-41

Angiotensin
Fragment ( 1-7 )
acetate

Asp-Arg-Val-Tyr-Ile-His-Pro-OH

5 MG

SM137-40

Angiotensin I
[Asn1,Val5,Asn9],
salmon

Asn-Arg-Val-Tyr-Val-His-Pro-Phe-Asn-Leu-OH

5 MG

160

SM137-36

Angiotensin I
[Val5,Asn9], bullfrog

Asp-Arg-Val-Tyr-Val-His-Pro-Phe-Asn-Leu-OH

5 MG

160

SM131-63

Angiotensin II
[Sar1,Ile8]

Sarcosine-Arg-Val-Tyr-Ile-His-Pro-Ile-OH

5 MG

160

SM131-49

Angiotensin II,
human

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH

5 MG

105

SM131-65

Angiotensin II-[Sar1]

Sarcosine-Arg-Val-Tyr-Ile-His-Pro-Phe-OH

5 MG

140

SM131-76

Angiotensin III,
human) /
Angiotensin II-[Des
Asp1]

Arg-Val-Tyr-Ile-His-Pro-Phe-OH

10 MG

140

SM131-82

Angiotensinogen
(1-14) Renin
Substrate (porcine)

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-
Val-Tyr-Ser-OH

10 MG

315

SM640-27

APP (354-371)

Lys-Ala-Val-Ile-Gln-His-Phe-Gln-Glu-Lys-Val-
Glu-Ser-Leu-Glu-Gln-Glu-Ala-OH

1 MG

235

SM640-27

APP (354-371)

Lys-Ala-Val-Ile-Gln-His-Phe-Gln-Glu-Lys-Val-
Glu-Ser-Leu-Glu-Gln-Glu-Ala-OH

5 MG

695

SM649-10

APP Beta
Secretase Inhibitor

Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-200-Val-
Ala-Glu-Phe-OH

1 MG

215

SM649-23

APP Gamma
Secretase Inhibitor

3-5difluorophenacetyl-Ala-S-Pheglycine-Methy
lester

5 MG

110

SM649-22

APP Gamma
Secretase Inhibitor

3-5difluorophenacetyl-Ala-S-Pheglycine-
t-butylester

5 MG

110

SM450-29

Arg-Gly-Asp-Ser
(RGDS)

Arg-Gly-Asp-Ser-OH

25 MG

145

SM641-14

[Gly22] Beta
Amyloid (1-40),
human ( Arctic )

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
y-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-Met-Val-Gly-Gly-Val-Val-OH

1 MG

325

SM641-14

[Gly22] Beta
Amyloid (1-40),
human ( Arctic )

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
y-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-Met-Val-Gly-Gly-Val-Val-OH

5 MG

1125

SM641-22

[Gly22] Beta
Amyloid (1-42),
human (Arctic)

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
y-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH

0.5 MG

295

SM641-22

[Gly22] Beta
Amyloid (1-42),
human (Arctic)

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
y-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH

1 MG

395

SM641-45

Beta Amyloid
[Glu11] (10-16),
human

Tyr-Glu-Val-His-His-Gln-Lys-OH

1 MG

100

SM641-45

Beta Amyloid
[Glu11] (10-16),
human

Tyr-Glu-Val-His-His-Gln-Lys-OH

5 MG

275

SM641-13

Beta Amyloid
[Nle35] (1-40),
human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-050-Val-Gly-Gly-Val-Val-OH

0.5 MG

230

SM641-13

Beta Amyloid
[Nle35] (1-40),
human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-050-Val-Gly-Gly-Val-Val-OH

1 MG

320

SM641-13

Beta Amyloid
[Nle35] (1-40),
human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-050-Val-Gly-Gly-Val-Val-OH

5 MG

1095

SM641-21

Beta Amyloid
(10-20), human

Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
-OH

0.5 MG

SM641-21

Beta Amyloid
(10-20), human

Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
-OH

1 MG

125

SM641-35

Beta Amyloid (1-16)
[Gln11], human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln
-Val-His-His-Gln-Lys-OH

1 MG

130

SM641-35

Beta Amyloid (1-16)
[Gln11], human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln
-Val-His-His-Gln-Lys-OH

5 MG

395

SM642-36

Beta Amyloid
(1-16), rat

Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Gl
u-Val-Arg-His-Gln-Lys-OH

1 MG

140

SM642-36

Beta Amyloid
(1-16), rat

Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Gl
u-Val-Arg-His-Gln-Lys-OH

5 MG

410

SM641-19

Beta Amyloid
(12-28), human

Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-OH

0.5 MG

SM641-19

Beta Amyloid
(12-28), human

Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-OH

1 MG

140

SM641-17

Beta Amyloid
(1-28), [Gln11],
human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-OH

0.5 MG

140

SM641-17

Beta Amyloid
(1-28), [Gln11],
human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-OH

1 MG

215

SM641-17

Beta Amyloid
(1-28), [Gln11],
human

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Gln
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-OH

5 MG

725

SM641-88

Beta Amyloid
(13-16), human

His-His-Gln-Lys-OH

1 MG

SM641-88

Beta Amyloid
(13-16), human

His-His-Gln-Lys-OH

5 MG

230

SM642-10

Beta Amyloid
(1-40), rat

Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Gl
u-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-
Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gl
y-Leu-Met-Val-Gly-Gly-Val-Val-OH

0.5 MG

245

SM642-10

Beta Amyloid
(1-40), rat

Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Gl
u-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-
Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gl
y-Leu-Met-Val-Gly-Gly-Val-Val-OH

1 MG

395

SM642-10

Beta Amyloid
(1-40), rat

Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Gl
u-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-
Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gl
y-Leu-Met-Val-Gly-Gly-Val-Val-OH

5 MG

1095

SM641-01

Beta Amyloid
[Glu11] (1-40),
human - HFIP

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-Met-Val-Gly-Gly-Val-Val-OH

0.5 MG

245

SM641-01

Beta Amyloid
[Glu11] (1-40),
human - HFIP

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu
-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gl
u-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-
Leu-Met-Val-Gly-Gly-Val-Val-OH

1 MG

395

SM641-15

Beta Amyloid
(1-42), human